HackerNews Summary (2023-04-30 04PM)

Source: EmuDeck 2.1 for Steam Deck launched

Summary
EmuDeck 2.1 for Steam Deck introduces a new EmuDeck Store where community-created games can be downloaded, a revamped interface that makes the emulator easier to navigate, new emulator support, and a USB Transfer Wizard for easy ROM transfer. Other changes include the ability to install experimental emulators, migrate installations between internal storage and microSD card, and add streaming services.

Fact
🎮 The new EmuDeck Store allows users to download community-created games like Cave Story or Demons of Asteborg.
💻 A revamped user interface helps to manage emulators and access the new homebrew store.
🕹️ New emulator support includes mGBA, MelonDS, Rosalie’s Mupen GUI, Pico-8 RetroArch core, Cemu, and Yuzu (Early Access).
📀 The USB Transfer Wizard makes it easy to import ROMs and BIOS files from a USB drive.
🔨 Additional changes include easier ways to manage emulators, migrate installations, and add streaming services to the Steam Deck.

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Source: CRISPR-Cas-amplified urinary biomarkers for multiplexed and portable cancer diagnostics

Summary
Peptides and oligonucleotides were synthesized and characterized for conjugation. The Cas12a fluorescent cleavage assay was used to detect Cas12a ssDNase activity triggered by modified DNA activators. Detection reactions were loaded onto a microfluidic Gene Expression IFC and analyzed.

Fact

🧬 Peptides and oligonucleotides were synthesized and HPLC purified by CPC Scientific and Integrated DNA Technologies (IDT), respectively.

🔬 Sequences of all molecules utilized were listed in Supplementary Tables 1 and 3.

🔬 Cas12a fluorescent cleavage assay was used to detect Cas12a ssDNase activity triggered by DNA activators.

📈 The initial reaction velocity (V 0 ) was calculated from the kinetics curve generated by the plate reader.

🧪 The Cas12a cleavage assay with lateral-flow readout used HybriDetect 1 lateral-flow strips for quantification.

🧪 DNA activator concentration or length was characterized to identify the optimal length for detection with Cas12a.

🧬 The Cas12 detection reactions were made into two separate mixes, assay mix and sample mix, for loading onto a microfluidic Gene Expression IFC (Fluidigm).

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Source: Maybe you should store passwords in plaintext.

Summary
Employees choose not to fix issues or write secure code at work as they believe it is not incentivized, and they won’t be rewarded for their efforts. They also store work credentials in plaintext, which is a potential security risk.

Facts

🤔 Employees choose not to fix a security vulnerability or unnecessary spend on AWS because it won’t be financially rewarded and could impact their performance review.

🐛 An employee doesn’t care about shipping code with bugs because it allows them to shirk actual development duties and receive praise for fixes.

💻 An employee sends out innocuous fixes to avoid doing their regular work and aims to be “perfectly mediocre.” They even plan to quit and negotiate a salary increase in a month.

🔑 These employees store work credentials in plaintext and don’t prioritize writing secure code because they don’t see any benefit in avoiding a security breach.

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Source: Banking crises rooted in a system that rewards excessive risk-taking – as First Republic’s precarious situation shows

Summary
First Republic Bank’s collapse could highlight how risky decisions at one bank can spread to the broader financial system. Incentive structures that encourage excessive risk-taking in the banking industry must be addressed to avoid history from repeating itself.

Facts

💰 Savings & loans banks’ executives lent to commercial real estate projects, taking on riskier loans to grow their portfolios, leading to the S&L crisis in the late 1980s.

🏦 Incentive structures encouraging risky strategies were also present in the 2008 crisis when lenders passed mortgages made to people who couldn’t afford them onto Wall Street firms.

💸 Executives at Bear Stearns and Lehman Brothers took bigger risks for immediate gains, leading to profits growth before the firms’ collapse.

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Source: xenohunter/bluesky-overhaul: UX improvements for Bluesky web app

Summary
Bluesky Overhaul is a Chrome extension with features such as emoji picker, auto-quote posting, keyboard navigation for photos, YouTube embeds in feed, Vim keybindings, and hide counts from profiles.

Fact

😃 The extension adds an emoji picker that allows users to choose from a palette of all available emojis and search them by name.

🌐 Auto quote-posting feature removes “staging.” from a link’s URL, clicks “Add link card” button for you and can remove the link from text after loading the card.

⌨️ Vim keybindings allow using j & k to traverse posts, l to like, and ? to lookup keybindings.

📷 In Keyboard navigation for photos, users can move via ← and → keys through images and close modal window by Esc.

🎬 YouTube embeds appear on YouTube links on profile and post pages, but not in search results yet.

👤 Hide followers, following, and posts counts from profiles is pretty self-explanatory.

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Source: Automated data insights

Summary
Efficiently gain insights and build intuitive dashboards with fast data processing.

Fact

🚀 Data processing is fast and efficient

📊 Dashboards are easy to create and understand

📈 Instant insights can be gained from the data

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